Selected Publications


      1. Xu Zhang,Kai Wen,Dongxiao Ding,Jintao Liu, Zhao Lei, Xiaoxuan Chen, Guozhu Ye,Jie Zhang,Heqing Shen,Changzhou Yan,Sjun Dong,Qiansheng Huang,Yi Lin.Size-dependent Adverse Effects of Microplastics on Intestinal Microbiota and Metabolic Homeostasis in the marine medaka (Oryzias melastigma). Environ Int. 2021, 151: 106452. 

  2. Ricardo David Avellán-Llaguno, Xiaobo Liu, Sijun Dong, Qiansheng Huang*. Occurrence and toxicity of perfluoroalkyl acids along the estuarine and coastal regions under varied environmental factors. Science of The Total Environment, 2021, 769, 144584. 

  3. Guozhu Ye#,*, Han Gao#, Zeming Wu, Jinsheng Chen, Jing Zhang, Qiansheng Huang*. Comprehensive metabolomics insights into benzo[a]pyrene-induced metabolic reprogramming related to H460 cell invasion and migration, Science of the Total Environment, 2021, DOI: 10.1016/j.scitotenv.2021.145763. 

  4. Guozhu Ye#,*, Bi-cheng Yang#, Han Gao, Zeming Wu, Jinsheng Chen, Xiao-yan Ai, Qiansheng Huang*, Metabolomics insights into oleate-induced disorders of phospholipid metabolism in macrophages, The Journal of Nutrition, DOI: 10.1093/jn/nxaa411. 

  5. Guozhu Ye#*, Han Gao#, Xu zhang, Xinyu Liu, Jinsheng Chen, Xu Liao, Han Zhang, Qiansheng Huang*. Aryl hydrocarbon receptor mediates benzo[a]pyrene-induced metabolic reprogramming in human lung epithelial BEAS-2B cells. Science of the Total Environment, 2020, 

  6. Yifei Qin, Jing Zhang, Ricardo David Avellán-Llaguno, Xu Zhang, Qiansheng Huang*. DEHP-elicited small extracellular vesicles miR-26a-5p promoted metastasis in nearby normal A549 cells. Environmental Pollution. 2021, 272: 116005. 

  7. Peiqiang Zhao#, Wenjia Lu#, Youwei Hong, Jinsheng Chen*, Sijun Dong*, Qiansheng Huang*. Long-term wet precipitation of PM2.5 disturbed the gut microbiome and inhibited the growth of marine medaka Oryzias melastigma. Science of The Total Environment, 2020, 142512. 

  8. Zhu, LT; Liu, XB; Huang, HN; Avellan-Llaguno, Ricardo David; Lazo, Mauricio Manuel Llaguno; Gaggero, Aldo; Rifo, Ricardo Soto; Patino, Leandro; Valencia-Avellan, Magaly; Diringer, Benoit; Huang, QS; Zhu, YG.Meteorological impact on the COVID-19 pandemic: A study across eight severely affected regions in South America. THE SCIENCE OF THE TOTAL ENVIRONMENT.2020,744,140881. 

  9. Avellan-Llaguno, Ricardo David; Liu, XB; Liu, LP; Dong, SJ; Huang, QS.   Elevated bioaccumulation of PFAAs in Oryzias melastigma following the increase of salinity is associated with the up-regulated expression of PFAA-binding proteins. SCIENCE OF THE TOTAL ENVIRONMENT.2020,725,138336. 

  10. Ye, GZ; Gao, H; Huang, QS; Lin, Y; Liao, X; Zhang, H; Yang, BC. Metabolomic Characterization of Metabolic Disturbances in the Extracellular Microenvironment of Oleate-Treated Macrophages Using Gas Chromatography-Mass Spectrometry. ANALYTICAL LETTERS.2020,53,2619-2635. 

  11. Qin, YF; Long, L; Huang, QS.Extracellular vesicles in toxicological studies: key roles in communication between environmental stress and adverse outcomes. JOURNAL OF APPLIED TOXICOLOGY.2020,40,1166-1182. 

  12. Ye, GZ; Gao, H; Wang, ZC; Lin, Y; Liao, X; Zhang, H; Chi, YL; Zhu, HM; Dong, SJ.PPAR alpha and PPAR gamma activation attenuates total free fatty acid and triglyceride accumulation in macrophages via the inhibition of Fatp1 expression. CELL DEATH & DISEASE.2019,10,39. 

  13. Ye, GZ; Gao, H; Lin, Y; Ding, DX; Liao, X; Zhang, H; Chi, YL; Dong, SJ.Peroxisome proliferator-activated receptor A/G reprogrammes metabolism associated with lipid accumulation in macrophages. METABOLOMICS.2019,15,36. 

  14. Ye, GZ; Chen, GY; Gao, H; Lin, Y; Liao, X; Zhang, H; Liu, XY; Chi, YL; Huang, QS; Zhu, HM; Fan, Y; Dong, S.Resveratrol inhibits lipid accumulation in the intestine of atherosclerotic mice and macrophages. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE.2019,23,4313-4325. 

  15. Wang, OG; Zhao, PL; Huang, QS; Chi, YL; Dong, SJ; Fan, JL. Bisphenol-A induces neurodegeneration through disturbance of intracellular calcium homeostasis in human embryonic stem cells-derived cortical neurons. CHEMOSPHERE.2019,229,618-630. 

  16. Wang, HG; Zhu, Y; Chi, YL; Dong, SJ.A human embryonic stem cell-based model for benzo[a]pyrene-induced embryotoxicity. REPRODUCTIVE TOXICOLOGY.2019,85,26-33. 

  17. Wang, HG; Chang, L; Aguilar, JS; Dong, SJ; Hong, YL. Bisphenol-A exposure induced neurotoxicity in glutamatergic neurons derived from human embryonic stem cells. ENVIRONMENT INTERNATIONAL.2019,127,324-332. 

  18. Ding, DX; Ye, GZ; Lin, Y; Lu, YY; Zhang, H; Zhang, X; Hong, ZY; Huang, QS; Chi, YL; Chen, JS; Dong, SJ.MicroRNA-26a-CD36 signaling pathway: Pivotal role in lipid accumulation in hepatocytes induced by PM2.5 liposoluble extracts. ENVIRONMENTAL POLLUTION.2019,248,269-278. 

  19. Chi, YL; Wang, HG; Lin, Y; Lu, YY; Huang, QS; Ye, GZ; Dong, SJ.Gut microbiota characterization and lipid metabolism disorder found in PCB77-treated female mice. TOXICOLOGY.2019,420,11-20. 

  20. Chi, YL; Lin, Y; Lu, YY; Huang, QS; Ye, GZ; Dong, SJ.Gut microbiota dysbiosis correlates with a low-dose PCB126-induced dyslipidemia and non-alcoholic fatty liver disease. SCIENCE OF THE TOTAL ENVIRONMENT.2019,653,274-282. 

  21. Ye, Gz; Ding, DX; Gao, H; Chi, YL; Chen, JS; Wu, ZM; Lin, Y; Dong, SJ.Comprehensive metabolic responses of HepG2 cells to fine particulate matter exposure: Insights from an untargeted metabolomics. SCIENCE OF THE TOTAL ENVIRONMENT.2019,691,874-884. 

  22. Lu, YY; Lin, Y; Ding, DX; Su, S; Chi, QQ; Zhang, YC; Sun, J; Zhang, X; Zhu, HM; Huang, QS; Chi, YL; Ye, GZ; Tao, S; Dong, SJ.MiR-26a functions as a tumor suppressor in ambient particulate matter-bound metal-triggered lung cancer cell metastasis by targeting LIN28B-IL6-STAT3 axis. ARCHIVES OF TOXICOLOGY.2018,92,1023-1035. 

  23. Huang, QS; Liu, YY; Dong, SJ.Emerging roles of long non-coding RNAs in the toxicology of environmental chemicals. JOURNAL OF APPLIED TOXICOLOGY.2018,38,934-943. 

  24. Huang, QS; Liu, YY; Chen, YJ; Fang, C; Chi, YL; Zhu, HM; Lin, Y; Ye, GZ; Dong, SJ.New insights into the metabolism and toxicity of bisphenol A on marine fish under long-term exposure. ENVIRONMENTAL POLLUTION.2018,242,914-921. 

  25. Chi, YL; Zhang, HT; Huang, QS; Lin, Y; Ye, GZ; Zhu, HM; Dong, SJ.Environmental risk assessment of selected organic chemicals based on TOC test and QSAR estimation models. JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA.2018,64,23-31. 

  26. Chi, YL; Lin, Y; Zhu, HM; Huang, QS; Ye, GZ; Dong, SJ.PCBs-high-fat diet interactions as mediators of gut microbiota dysbiosis and abdominal fat accumulation in female mice. ENVIRONMENTAL POLLUTION.2018,239,332-341. 

  27. Chi, YL; Huang, QS; Lin, Y; Ye, GZ; Zhu, HM; Dong, SJ.Epithelial-mesenchymal transition effect of fine particulate matter from the Yangtze River Delta region in China on human bronchial epithelial cells. JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA.2018,66,155-164. 

  28. Chen, GY; Ye, GZ; Zhang, XB; Liu, XX; Tu, YF; Ye, ZJ; Liu, JC; Guo, Q; Wang, ZG; Wang, L; Dong, SJ; Fan, YH.Metabolomics Reveals Protection of Resveratrol in Diet-Induced Metabolic Risk Factors in Abdominal Muscle. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY.2018,45,1136-1148. 

  29. Lin, Y; Ding, DX; Huang, QS; Liu, Q; Lu, HY; Lu, YY; Chi, YL; Sun, X; Ye, GZ; Zhu, HM; Wei, J; Dong, SJ.Downregulation of miR-192 causes hepatic steatosis and lipid accumulation by inducing SREBF1: Novel mechanism for bisphenol A-triggered non-alcoholic fatty liver disease. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS.2017,1862,869-882. 

  30. Huang, QS; Chi, YL; Deng, JJ; Liu, YY; Lu, YY; Chen, JS; Dong, SJ.Fine particulate matter 2.5 exerted its toxicological effect by regulating a new layer, long non-coding RNA. SCIENTIFIC REPORTS.2017,7,9392. 

  31. Huang, QS; Chen, YJ; Lin, LF; Liu, YY; Chi, YL; Lin, Y; Ye, GZ; Zhu, HM; Dong, SJ.Different effects of bisphenol a and its halogenated derivatives on the reproduction and development of Oryzias melastigma under environmentally relevant doses. SCIENCE OF THE TOTAL ENVIRONMENT.2017,595,752-758. 

  32. Huang, QS; Chen, YJ; Chen, QH; Zhang, HT; Lin, Y; Zhu, MB; Dong, SJ.Dioxin-like rather than non-dioxin-like PCBs promote the development of endometriosis through stimulation of endocrine-inflammation interactions. ARCHIVES OF TOXICOLOGY.2017,91,1915-1924. 

  33. Huang, QS.Mediating Roles of PPARs in the Effects of Environmental Chemicals on Sex Steroids. PPAR RESEARCH.2017,2017,2017:3203161. 

  34. Chi, YL; Wu, ZJ; Zhong, Y; Dong, SJ.Enantiomeric resolution, stereochemical assignment and toxicity evaluation of TPA enantiomers. BIOMEDICAL CHROMATOGRAPHY.2017,31,8.